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Posts Tagged ‘AIDS’

Goldman: Cecil Medicine, 23rd ed. Copyright © 2007 Saunders, An Imprint of Elsevier SUGGESTED READINGS Carrington M, Martin MP: The impact of variation at the KIR gene cluster on human disease.  Curr Top Microbiol Immunol  2006; 298:225-257.A thorough review of the complex genetics of killer inhibitory receptors, an important group of ligands for HLA class I molecules with emerging […]

Goldman: Cecil Medicine, 23rd ed. Copyright © 2007 Saunders, An Imprint of Elsevier Chapter 43 – THE MAJOR HISTOCOMPATIBILITY COMPLEX Peter K. Gregersen HUMAN LEUKOCYTE ANTIGENS The major histocompatibility complex (MHC) occupies a unique position in the nexus between clinical medicine, immunology, and genetics. Hundreds of diseases and clinical phenotypes have been associated with genes located within the […]

Goldman: Cecil Medicine, 23rd ed. Copyright © 2007 Saunders, An Imprint of Elsevier ASSOCIATION STUDIES Despite this uncertainty, there has been significant progress identifying genes that contribute to the population risk for common diseases. Nearly all examples have been discovered through epidemiologic association studies of common genetic variation. Genetic association studies are simple in conception. […]

Goldman: Cecil Medicine, 23rd ed. Copyright © 2007 Saunders, An Imprint of Elsevier SUGGESTED READINGS Challacombe S, Coogan M, Williams D, Greenspan J.: Overview and research agenda arising from the 5th World Workshop on Oral Health and Disease in AIDS.  Adv Dent Res  2006; 19:5-9.A comprehensive view of HIV-related lesions Gonsalves WC, Chi AC, Neville BW: Common oral lesions: Part I. Superficial mucosal lesions. […]

Goldman: Cecil Medicine, 23rd ed. Copyright © 2007 Saunders, An Imprint of Elsevier Section XXVI – Eye, Ear, Nose, and Throat Diseases Chapter 449 – DISEASES OF THE VISUAL SYSTEM Aaron Fay GENERAL APPROACH TO VISUAL LOSS Diminished vision often brings patients to medical attention. The cause may be primarily ophthalmic (e.g., cataract) or systemic (e.g., hypertensive retinal detachment). Frequently, […]

Goldman: Cecil Medicine, 23rd ed. Copyright © 2007 Saunders, An Imprint of Elsevier Chapter 443 – NUTRITION- AND ALCOHOL-RELATED NEUROLOGIC DISORDERS John C.M. Brust Neurologic disease is associated with deficiency of certain nutrients. In developing countries, such deficiencies are usually the result of starvation or a restricted diet. In developed countries, the major causes are alcoholism ( Chapter […]

Goldman: Cecil Medicine, 23rd ed. Copyright © 2007 Saunders, An Imprint of Elsevier DRUGS OF ABUSE Heroin and Other Opioids   Definition Opioids, including naturally occurring alkaloids (opiates derived from the poppy plant Papaver somniferum), semisynthetic compounds (chemically altered alkaloids), and synthetic agents, are potent analgesics and produce an intense euphoria associated with nausea, drowsiness, […]

Goldman: Cecil Medicine, 23rd ed. Copyright © 2007 Saunders, An Imprint of Elsevier Chapter 437 – MENINGITIS: BACTERIAL, VIRAL, AND OTHER Morton N. Swartz BACTERIAL MENINGITIS Definition Meningitis is an inflammation of the arachnoid, the pia mater, and the intervening cerebrospinal fluid (CSF). The inflammatory process extends throughout the subarachnoid space about the brain and spinal cord and […]

Goldman: Cecil Medicine, 23rd ed. Copyright © 2007 Saunders, An Imprint of Elsevier SUGGESTED READINGS Bower M, Palmieri C, Dhillon T.: AIDS-related malignancies: Changing epidemiology and the impact of highlly active antiretroviral therapy.  Curr Opin Infect Dis  2006; 19:14-19.Review of the postive impact of HAART on the incidence of AIDS-related cancers Cattelan AM, Calabro ML, De Rossi A, et al: Long-term clinical outcome of […]

Goldman: Cecil Medicine, 23rd ed. Copyright © 2007 Saunders, An Imprint of Elsevier Chapter 417 – NEUROLOGIC COMPLICATIONS OF HUMAN IMMUNODEFICIENCY VIRUS INFECTION Joseph R. Berger   Avindra Nath The neurologic complications of human immunodeficiency virus (HIV) infection can affect any portion of the neuraxis. They can be broadly divided into two large groups: those that are the consequence of HIV […]

Goldman: Cecil Medicine, 23rd ed. Copyright © 2007 Saunders, An Imprint of Elsevier Chapter 416 – HEMATOLOGY AND ONCOLOGY IN PATIENTS WITH HUMAN IMMUNODEFICIENCY VIRUS INFECTION Paul A. Volberding Hematologic disorders and unusual cancers were important and early warnings of the human immunodeficiency virus (HIV) epidemic and remain significant clinical problems despite progress in antiretroviral (ARV) drug development. […]

Goldman: Cecil Medicine, 23rd ed. Copyright © 2007 Saunders, An Imprint of Elsevier SUGGESTED READINGS Grant AD, Charalambous S, Fielding KL, et al: Effect of routine isoniazid preventive therapy on tuberculosis incidence among HIV-infected men in South Africa: A novel randomized incremental recruitment study.  JAMA  2005; 293:2719-2725.Enrollment in a clinic offering primary isoniazid preventive therapy to HIV-infected adults reduced tuberculosis incidence […]

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