Category: Oxford Handbook Of Dialysis

Editors: Levy, Jeremy; Morgan, Julie; Brown, Edwina Title: Oxford Handbook of Dialysis, 2nd Edition Copyright ©2004 Oxford University Press > Table of Contents > Part 9 – Complications of ESRD: Fluid overload Part 9 Complications of ESRD: Fluid overload Can be symptomatic, asymptomatic but clinically detectable or covert (usually manifesting solely as hypertension). Symptoms and […]

Editors: Levy, Jeremy; Morgan, Julie; Brown, Edwina Title: Oxford Handbook of Dialysis, 2nd Edition Copyright ©2004 Oxford University Press > Table of Contents > Part 8 – Complications of ESRD: anaemia > High ferritin and low transferrin saturation index High ferritin and low transferrin saturation index Some patients have a high serum ferritin (often <1000 […]

Editors: Levy, Jeremy; Morgan, Julie; Brown, Edwina Title: Oxford Handbook of Dialysis, 2nd Edition Copyright ©2004 Oxford University Press > Table of Contents > Part 8 – Complications of ESRD: anaemia > Erythropoietin: failure to respond (resistance) Erythropoietin: failure to respond (resistance) Most common cause is iron deficiency, often induced by the rise in Hb. […]

Editors: Levy, Jeremy; Morgan, Julie; Brown, Edwina Title: Oxford Handbook of Dialysis, 2nd Edition Copyright ©2004 Oxford University Press > Table of Contents > Part 8 – Complications of ESRD: anaemia > Iron supplements: oral iron Iron supplements: oral iron All dialysis patients should receive iron unless they have documented excessive iron stores (ferritin >800 […]

Editors: Levy, Jeremy; Morgan, Julie; Brown, Edwina Title: Oxford Handbook of Dialysis, 2nd Edition Copyright ©2004 Oxford University Press > Table of Contents > Part 8 – Complications of ESRD: anaemia > Intravenous iron Intravenous iron Efficacious in all studies in increasing Hb, increasing ferritin and transferrin saturation index, and reducing EPO requirements. Potential concerns […]

Editors: Levy, Jeremy; Morgan, Julie; Brown, Edwina Title: Oxford Handbook of Dialysis, 2nd Edition Copyright ©2004 Oxford University Press > Table of Contents > Part 8 – Complications of ESRD: anaemia > Intravenous iron preparations: iron sucrose Intravenous iron preparations: iron sucrose Iron III hydroxide sucrose complex (iron sucrose or saccharate) Widely used in Europe […]

Editors: Levy, Jeremy; Morgan, Julie; Brown, Edwina Title: Oxford Handbook of Dialysis, 2nd Edition Copyright ©2004 Oxford University Press > Table of Contents > Part 8 – Complications of ESRD: anaemia > Intravenous iron preparations: iron gluconate and dextran Intravenous iron preparations: iron gluconate and dextran Sodium ferric gluconate (Ferrecit) Increasingly used. Widely available in […]

Editors: Levy, Jeremy; Morgan, Julie; Brown, Edwina Title: Oxford Handbook of Dialysis, 2nd Edition Copyright ©2004 Oxford University Press > Table of Contents > Part 8 – Complications of ESRD: anaemia > Erythropoietin: administration Erythropoietin: administration EPO is available as vials containing 1–10000 units per ml, as larger volume multidose vials, as pre-filled syringes with […]

Editors: Levy, Jeremy; Morgan, Julie; Brown, Edwina Title: Oxford Handbook of Dialysis, 2nd Edition Copyright ©2004 Oxford University Press > Table of Contents > Part 8 – Complications of ESRD: anaemia > Darbepoietin (Aranesp) Darbepoietin (Aranesp) Comes in a range of colour-coded pre-filled syringes, ranging from 10–150 µg. Should be stored at 2–8°C, in its […]

Editors: Levy, Jeremy; Morgan, Julie; Brown, Edwina Title: Oxford Handbook of Dialysis, 2nd Edition Copyright ©2004 Oxford University Press > Table of Contents > Part 8 – Complications of ESRD: anaemia > Erythropoietin: initiating therapy Erythropoietin: initiating therapy Patients must have adequate iron stores prior to starting EPO or darbepoietin. Serum ferritin should be >200 […]

Editors: Levy, Jeremy; Morgan, Julie; Brown, Edwina Title: Oxford Handbook of Dialysis, 2nd Edition Copyright ©2004 Oxford University Press > Table of Contents > Part 8 – Complications of ESRD: anaemia > Erythropoietin: maintenance therapy Erythropoietin: maintenance therapy Hb level should be monitored monthly in HD patients and 2 monthly in predialysis or PD patients. […]

Editors: Levy, Jeremy; Morgan, Julie; Brown, Edwina Title: Oxford Handbook of Dialysis, 2nd Edition Copyright ©2004 Oxford University Press > Table of Contents > Part 8 – Complications of ESRD: anaemia > Erythropoietin: side-effects Erythropoietin: side-effects Hypertension is the most common complication (20–50% patients): associated with rate of rise in Hb, absolute level of Hb […]

Editors: Levy, Jeremy; Morgan, Julie; Brown, Edwina Title: Oxford Handbook of Dialysis, 2nd Edition Copyright ©2004 Oxford University Press > Table of Contents > Part 8 – Complications of ESRD: anaemia > Erythropoietin: target haemoglobin Erythropoietin: target haemoglobin Target Hb remains controversial. Tends to be governed by economic factors; there is no randomized clinical trial […]

Editors: Levy, Jeremy; Morgan, Julie; Brown, Edwina Title: Oxford Handbook of Dialysis, 2nd Edition Copyright ©2004 Oxford University Press > Table of Contents > Part 8 – Complications of ESRD: anaemia > Assessment of anaemia and haemolysis Assessment of anaemia and haemolysis Investigating anaemia in ESRD Should be performed when Hb < 13 g/dl (men) […]

Editors: Levy, Jeremy; Morgan, Julie; Brown, Edwina Title: Oxford Handbook of Dialysis, 2nd Edition Copyright ©2004 Oxford University Press > Table of Contents > Part 8 – Complications of ESRD: anaemia > Assessment of iron stores Assessment of iron stores Functional and absolute iron deficiency are important causes of anaemia in ESRD, and especially important […]

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