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Category: Cecil Medicine, 23rd Edition

Goldman: Cecil Medicine, 23rd ed. Copyright © 2007 Saunders, An Imprint of Elsevier SUGGESTED READINGS Aberer W, Bircher A, Romano A, et al: Drug provocation testing in the diagnosis of drug hypersensitivity reactions: General considerations.  Allergy  2003; 58:854-863.An overview of this approach Brockow K, Christiansen C, Kanny G, et al: Management of hypersensitivity reactions to iodinated contrast media.  Allergy  2005; 60:150-158.A comprehensive review Gruchalla RS: Drug allergy.  J […]

Goldman: Cecil Medicine, 23rd ed. Copyright © 2007 Saunders, An Imprint of Elsevier Chapter 276 – MASTOCYTOSIS Cem Akin Definition Mastocytosis is a heterogeneous group of disorders characterized by pathologic accumulation of mast cells in tissues such as skin and bone marrow. According to the classification of the World Health Organization (WHO), based on clinical presentation and pathologic […]

Goldman: Cecil Medicine, 23rd ed. Copyright © 2007 Saunders, An Imprint of Elsevier SUGGESTED READINGS Akin C, Metcalfe DD: Systemic mastocytosis.  Annu Rev Med  2004; 55:419.A concise review Akin C, Metcalfe DD: The biology of Kit in disease and the application of pharmacogenetics.  J Allergy Clin Immunol  2004; 114:13.A review on potential use of tyrosine kinase inhibitors based on mutations in KIT Barbie […]

Goldman: Cecil Medicine, 23rd ed. Copyright © 2007 Saunders, An Imprint of Elsevier Chapter 274 – SYSTEMIC ANAPHYLAXIS, FOOD ALLERGY, AND INSECT STING ALLERGY   Lawrence B. Schwartz   Definition   Systemic anaphylaxis, a form of immediate hypersensitivity, arises when mast cells and possibly basophils are provoked to secrete mediators with potent vasoactive and smooth muscle contractile activities […]

Goldman: Cecil Medicine, 23rd ed. Copyright © 2007 Saunders, An Imprint of Elsevier    REFERENCES 1. Leung DYM, Sampson HA, Yunginger JW, et al: Effect of anti-IgE therapy in patients with peanut allergy.  N Engl J Med  2003; 348:986-993. Email to Colleague Print Version Copyright © 2007 Elsevier Inc. All rights reserved. –

Goldman: Cecil Medicine, 23rd ed. Copyright © 2007 Saunders, An Imprint of Elsevier    REFERENCES 1. Mazumder DNG, De KB, Santra A, et al: Randomized placebo-controlled trial of 2,3-dimercapto-1-propanesulfonate (DMPS) in therapy of chronic arsenicosis due to drinking arsenic-contaminated water.  J Toxicol Clin Toxicol  2001; 39:665-674. 2. Koller WC, Lyons KE, Truly W: Effect of levodopa treatment for parkinsonism in welders: A double-blind study. […]

Goldman: Cecil Medicine, 23rd ed. Copyright © 2007 Saunders, An Imprint of Elsevier SUGGESTED READINGS Bilo BM, Rueff F, Mosbech H, et al: Diagnosis of hymenoptera venom allergy.  Allergy  2005; 60:1339-1349.Discusses the diagnostic approach to patients with a history of a systemic sting reaction Brown SK, Blackman KE, Stenlake V, Heddle RJ: Insect sting anaphylaxis: Prospective evaluation of treatment with intravenous adrenaline and volume resuscitation. […]

Goldman: Cecil Medicine, 23rd ed. Copyright © 2007 Saunders, An Imprint of Elsevier Chapter 275 – DRUG ALLERGY   Leslie C. Grammer   Definition   Adverse drug reactions (ADRs) are recognized as an important public health problem in that they may be life-threatening. An ADR is defined by the World Health Organization (WHO) as an unintended, noxious response […]

Goldman: Cecil Medicine, 23rd ed. Copyright © 2007 Saunders, An Imprint of Elsevier    REFERENCES 1. Premawardhena AP, de Silva CE, Fonseka MM, et al: Low dose subcutaneous epinephrine to prevent acute adverse reactions to antivenom serum in people bitten by snakes: Randomised, placebo-controlled trial.  BMJ  1999; 318:1041-1043. Email to Colleague Print Version Copyright © 2007 Elsevier Inc. All rights reserved. […]

Goldman: Cecil Medicine, 23rd ed. Copyright © 2007 Saunders, An Imprint of Elsevier Chapter 272 – ALLERGIC RHINITIS AND SINUSITIS   Larry Borish   Definition   Allergic rhinitis (AR) refers to the nasal and ocular symptoms that occur as a result of the development of an inflammatory hypersensi-tivity reaction to aeroallergens deposited on the nasal mucosa and conjunctiva. […]

Goldman: Cecil Medicine, 23rd ed. Copyright © 2007 Saunders, An Imprint of Elsevier    REFERENCES 1. Woodcock A, Forster L, Matthews E, et al: Control of exposure to mite allergen and allergen-impermeable bed covers for adults with asthma.  N Engl J Med  2003; 349:225-236. 2. Terreehorst I, Hak E, Oosting AJ, et al: Evaluation of impermeable covers for bedding in patients with allergic rhinitis.  N […]

Goldman: Cecil Medicine, 23rd ed. Copyright © 2007 Saunders, An Imprint of Elsevier SUGGESTED READINGS Borish L: Allergic rhinitis: Systemic inflammation and implications for management.  J Allergy Clin Immunol  2003; 112:1021-1031.A discussion of pathogenesis and its influence on treatment options Plaut M, Valentine MD: Allergic rhinitis.  N Engl J Med  2005; 353:1934-1944.Reviews the evaluation of and pharmacotherapies available for this condition Prenner […]

Goldman: Cecil Medicine, 23rd ed. Copyright © 2007 Saunders, An Imprint of Elsevier Chapter 273 – URTICARIA AND ANGIOEDEMA Stephen C. Dreskin    URTICARIA Urticaria (hives) are pruritic, edematous, erythematous, blanching papules that are round or oval in shape, have pale raised centers (wheals), are of several millimeters to a few centimeters in size, and are transient, lasting […]

Goldman: Cecil Medicine, 23rd ed. Copyright © 2007 Saunders, An Imprint of Elsevier    REFERENCES 1. Grattan CE, O’Donnell BF, Francis DM, et al: Randomized double-blind study of cyclosporin in chronic “idiopathic” urticaria.  Br J Dermatol  2000; 143:365-372. 2. Kunschak M, Engl W, Maritsch F, et al: A randomized, controlled trial to study the efficacy and safety of C1 inhibitor concentrate in treating hereditary angioedema. […]

Goldman: Cecil Medicine, 23rd ed. Copyright © 2007 Saunders, An Imprint of Elsevier SUGGESTED READINGS   Bork K, Meng G, Staubach P, Hardt J: Hereditary angioedema: New findings concerning symptoms, affected organs, and course.  Am J Med  2006; 119:267-274.A comprehensive review   Dibbern Jr DA, Dreskin SC: Urticaria and angioedema: An overview.  Immunol Allergy Clin North Am  2004; 24:141-162.An overview of acute and chronic urticaria […]

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